For deep-tech startups, university spinouts and research-driven founders, NSF SBIR/STTR funding has long been one of the most important sources of non-dilutive capital in the country.
Now, the program is officially back.
The U.S. National Science Foundation recently relaunched its Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, reopening a major funding pathway for startups developing breakthrough technologies rooted in science and engineering.
Why it matters
Unlike venture capital, NSF SBIR/STTR funding does not require founders to give up equity.
Instead, the program supports high-risk, high-impact research and development with strong commercial potential. Phase I awards can provide up to $305,000 to help startups validate technologies and move closer to commercialization.
NSF is not looking for incremental product improvements or routine software development. The strongest applications typically combine strong scientific or engineering innovation, meaningful technical risk and a clear market opportunity.
Step 1: Determine project fit
Before applying, founders should review NSF’s project fit guidance to determine whether their technology aligns with program priorities.
Competitive projects typically include:
- Novel technologies rooted in science or engineering
- Significant research and development challenges
- Strong commercialization potential
- Broad societal or economic impact
Step 2: Submit a Project Pitch
One of the biggest changes in the relaunched program is the required Project Pitch process.
Instead of starting with a lengthy proposal, companies now begin with a short pitch outlining:
- The technology
- The problem being solved
- The proposed R&D effort
- The commercial opportunity
If NSF determines the project is a strong fit, the company receives an invitation to submit a full proposal.
Step 3: Prepare the full proposal
Invited companies move into the formal proposal stage, which includes:
- A technical research plan
- Commercialization strategy
- Budget and milestones
- Supporting company information
Companies can review NSF’s full proposal guidance before beginning the submission process.
Step 4: Proposal review and decision
Full proposals undergo NSF’s merit review process, which evaluates both technical excellence and commercial potential.
Even companies that are not selected for funding receive reviewer feedback that can help strengthen future submissions and commercialization strategy.
New pilot focuses on scientific instrumentation
Alongside the relaunch, NSF also announced a new pilot program focused on scientific instrumentation and research-enabling technologies.
The initiative is part of a broader $250 million investment to restart and expand the SBIR/STTR ecosystem.
The pilot is designed to support startups developing:
- Advanced scientific instruments
- Novel experimental platforms
- Research-enabling technologies
- Tools that accelerate scientific discovery
For founders building technologies that enable science itself, this could represent a significant new funding pathway.
How the Park can help
Strong NSF applications rarely begin with the proposal itself.
They begin with customer discovery, commercialization strategy and a clear understanding of how the technology solves a meaningful problem.
KU Innovation Park’s business services team works with startups and university innovators throughout the commercialization journey, including evaluating project fit, strengthening commercialization strategies and helping teams prepare for funding opportunities like NSF SBIR/STTR.



















